A brand new collaborative article, at J. Exp. Clin. Cancer Res., is now available on-line through the journal website
01/27/2024We are really glad to announce here that our last collaborative article at the J. Exp. Clin. Cancer Res., entitled "Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy" and authored by S. Alcalá, L. Villarino, [...] (25 further authors), J. L. Mascareñas and B. Sainz J., is already available through the journal website as a gold-open access paper.
Do not miss these latest results for this joint project among B. Sainz Jr. research group and ours!
Abstract: The coordination complex Ru1 represents not only an exciting new anti-cancer agent, but also a molecular tool to dissect the role of OXPHOS in CSCs. Results indicating that the compound is safe, non-toxic and highly effective in vivo are extremely exciting, and have allowed us to uncover unprecedented mechanistic possibilities to fight different cancer types based on targeting CSC OXPHOS