A brand new chembio field paper is on-line, available at Chem. Eur. J.
04/01/2020Continuing with the nice results coming out during the beginning of 2020, we are very pleased to share our last publication at Chem. Eur. J., entitled "Assembly of a ternary metallopeptide complex at specific DNA sites mediated by an AT‐Hook adaptor" and authored by S. Learte-Aymamí, J. Rodríguez, E. Vázquez and J. L. Mascareñas.
Abstract:We describe the nickel(II)‐mediated self‐assembly of a multimeric DNA binder composed by two metal‐chelating peptides derived from a bZIP transcription factor ( brHis 2 ) and one short AT‐hook domain equipped with two bipyridine ligands ( HkBpy 2 ). These peptides reversibly assemble in the presence of Ni(II) ions at selected DNA sequences of 13 base pairs.
External link: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.202001277